A brain drain is said to occur when highly educated and highly skilled people leave their native region to pursue opportunities elsewhere. Discussion and analysis of a brain drain and its consequences usually occur in an international context, but in a large nation such as the United States it may be useful to examine the migration of the highly educated from one region to another. Data from the American Community Survey (U.S. Bureau of the Census) are used below to address the question of whether or not New Mexico is experiencing a brain drain. A brief discussion of the possible consequences of a brain drain precedes the data analysis.